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ALLEN GI, TSUKAHARA N: Cerebrocerebellar communication systems Physiol Rev 54:957, 1974 BABINSKI J: De l asynergie cerebelleuse Rev Neurol 7:806, 1899 CHAMBERS WW, SPRAGUE JM: Functional localization in the cerebellum: I Organization in longitudinal cortico-nuclear zones and their contribution to the control of posture, both extrapyramidal and pyramidal J Comp Neurol 103:104, 1955 CHAMBERS WW, SPRAGUE JM: Functional localization in the cerebellum: II Somatotopic organization in cortex and nuclei Arch Neurol Psychiatry 74:653, 1955 DIENER HC, DICHGANS J: Pathophysiology of cerebellar ataxia Mov Disord 7:95, 1992 EVARTS EV, THACH WT: Motor mechanism of the CNS: Cerebrocerebellar interrelations Annu Rev Physiol 31:451, 1969 GILMAN S: Cerebellar control of movement Ann Neurol 35:3, 1994 GILMAN S, BLOEDEL J, LECHTENBERG R: Disorders of the Cerebellum Philadelphia, Davis, 1980, pp 159 177 HALLETT M, BERARDELLI A, MATHESON J, et al: Physiological analysis of simple rapid movement in patients with cerebellar de cits J Neurol Neurosurg Psychiatry 53:124, 1991 HALLETT M, SHAHANI BT, YOUNG RR: EMG analysis of patients with cerebellar de cits J Neurol Neurosurg Psychiatry 38:1163, 1975 HOLMES G: The cerebellum of man: Hughlings Jackson Lecture Brain 62: 1, 1939 JANSEN J, BRODAL A: Aspects of Cerebellar Anatomy Oslo, Johan Grundt Tanum Forlag, 1954 KANDEL ER, SCHWARTZ JH, JESSEL TM(eds): Principles of Neural Science, 4th ed New York, McGraw-Hill, 2000 LEINER HC, LEINER AL, DOW RS: Does the cerebellum contribute to mental skills Behav Neurosci 100:443, 1986 SCHMAHMANN JD, SHERMAN JC: The cerebellar cognitive affective syndrome Brain 121:561, 1998 SPRAGUE JM, CHAMBERS WW: Control of posture by reticular formation and cerebellum in the intact, anesthetized and unanesthetized and in the decerebrated cat Am J Physiol 176:52, 1954 STEWART TG, HOLMES G: Symptomatology of cerebellar tumors: A study of forty cases Brain 27:522, 1904 THACH WT JR, GOODKIN HP, KEATING JG: The cerebellum and the adaptive coordination of movement Annu Rev Neurosci 150:403, 1992 THACH WT JR, MONTGOMERY EB Jr: Motor system, in Pearlman AL, Collins RC (eds): Neurobiology of Disease New York, Oxford University Press, 1992, pp 168 196 URBAN PP, MARX J, HUNSCHE S, et al: Cerebellar speech representation Arch Neurol 60:965, 2003.

2 Contained in the file specified by the first non-option argument to the Perl interpreter 3 Piped in to the interpreter via the standard input This works either if there are no arguments or if there is a command line argument Perl supports a number of command line options These can either be specified on the actual command line, if you are manually executing Perl, or they can be specified within the #! line at the start of the script The #! line is always processed by Perl, irrespective of how the script is invoked If you are using this method, be aware that some Unix systems place a limit on the size of the line usually 32 characters You will therefore need to make sure you place the most significant of the command line options early in the arguments Although there are no hard-and-fast rules, the -T (taint checking) and -I arguments should be placed as early as possible in the command line options, irrespective of where they are specified Whether they are specified on the command line or within the #! line, command line options can either be selected individually, as in,

0f out The areaunderthe curve from zero stress to thepoint of It ruptureis calledthe modulusof toughness the material providesa measure the energyper unit volumerequired to of lfr ol causethe materialto ruptureAs such,it is representative Vttt:; I ittllt LJo the material'sability to withstand an impact loadUsenufol If C: l0 s farad,use the fbllowing currentdata to develop mericalintegrationto computethe modulusof toughness curve seenin Fig Pl 8 I 6b the stress-strain a plot of voltageversustime: Ittl7 If the velocity distributionof a fluid flowing through a pipe is known (Fig Pl8l7), the flow rate Q (thatis,the 04 06 t'3 0 a2 03683 038t9 0 2 2 8 2 volume of water passingthroughthe pipe per unit time)can i, Io-3 A o2 and be computedby Q : J u tl A, where u is the velocity, A ol is the pipe's cross-sectional area(To graspthe meaning ) 12 t,s 0B bethis relationshipphysically,recall the close connection i, Io-3 A 0 0486 00082 0 )441 tween summation and integration) For a circular pipe, A: r12 anddA:2rr dr Therefore Itll5 The work doneon an object is equalto the fbrce times rl the distancemoved in the direction of the force The velocO -- I u(2rr)dr ity of an object in the dircction of a fbrce is given by JIJ lltl{ If a capacitorinitially holds no charge,the voltage acrossit as a function of time can be computedas u:4t u:16*(4-r)t 0<t<4 4<t<14

The subject of tremor is considered at this point because of its association with diseases of the basal ganglia and cerebellum In addition, a group of miscellaneous movement disorders myoclonus, facial and cervical dyskinesias, occupational spasms (focal dystonias), and tics are described in this chapter These disorders are largely involuntary in nature and can be quite disabling, but they have an uncertain pathologic basis and an inde nite relationship to the extrapyramidal motor disorders or to other standard categories of neurologic disease They are brought together here mainly for convenience of exposition

$ perl -p -ibak -e "s/foo/bar/g"

The following types of tremor, the features of which are summarized in Table 6-1, are the ones encountered most frequently in clinical practice In clinical analysis, they are usually distinguishable on the basis of (1) rhythmicity, (2) amplitude, (3) frequency, and (4) relation to movement, postural set, and relaxation Such analysis also differentiates tremors from a large array of nontremorous states, such as fasciculations, sensory ataxia, myoclonus, asterixis, epilepsia partialis continua, clonus, and shivering

where r is in m/s Determinethe work if a constantforce of 200 N is appliedfor all r llt16 A rod subject an axial load (Fig Pl8i6n) will be to curvein Fi P I 8 I 60 deformedas shownin the stress-strain

or they can be combined:

.

r where is the radial distancemeasuredoutward from the ol is center thepipeIf the velocilydistribution given by

$ perl -pibak -e "s/foo/bar/g"